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A phase I trial of deep brain stimulation of memory circuits in Alzheimer's disease

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A phase I trial of deep brain stimulation of memory circuits in Alzheimer's disease

Auteurs : Adrian W. Laxton [Canada] ; David F. Tang-Wai [Canada] ; Mary Pat Mcandrews [Canada] ; Dominik Zumsteg [Suisse] ; Richard Wennberg [Canada] ; Ron Keren [Canada] ; John Wherrett [Canada] ; Gary Naglie [Canada] ; Clement Hamani [Canada] ; Gwenn S. Smith [États-Unis] ; Andres M. Lozano [Canada]

Source :

[ 0364-5134 ]

RBID : ISTEX:D5AB9FE76587154004A039ACD27CF7D5098FB88D

Abstract

Alzheimer disease (AD) is characterized by functional impairment in the neural elements and circuits underlying cognitive and memory functions. We hypothesized that fornix/hypothalamus deep brain stimulation (DBS) could modulate neurophysiological activity in these pathological circuits and possibly produce clinical benefits.

Url:

https://api-v5.istex.fr/document/D5AB9FE76587154004A039ACD27CF7D5098FB88D/fulltext/pdf

DOI: 10.1002/ana.22089

Affiliations:

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Le document en format XML

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<front><div type="abstract">Alzheimer disease (AD) is characterized by functional impairment in the neural elements and circuits underlying cognitive and memory functions. We hypothesized that fornix/hypothalamus deep brain stimulation (DBS) could modulate neurophysiological activity in these pathological circuits and possibly produce clinical benefits.</div>
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	La maladie de Parkinson au Canada (serveur d'exploration)
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La maladie de Parkinson au Canada (serveur d'exploration)

A phase I trial of deep brain stimulation of memory circuits in Alzheimer's disease

A phase I trial of deep brain stimulation of memory circuits in Alzheimer's disease

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Abstract

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